How Vitamin B12 interacts with phenytoin
Interaction Type: Depletions
Interaction Rating: Study Supported

Phenytoin may decrease the absorption of vitamin B12 into certain cells in the body. Supplementation with the affected nutrient may be necessary.(1)
 
References
  1. View Abstract:  Latham J, et al. Effects of Phenytoin Sodium On Doubling Time, Deoxyuridine Suppression, 3H-Methotrexate Uptake and 57Co-cyanocobalamin Uptake in HL60 Cells. Clin Lab Haematol. 1990;12(1):67-75.
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