How Vitamin B12 interacts with Biguanides
Interaction Type: Depletions
Interaction Rating: Study Supported
In one study, 30% of patients taking metformin developed a decreased ability to absorb vitamin B12. Supplementation with the affected nutrient may be necessary.(1)
These drugs include metformin.
 
References
  1. View Abstract:  Adams JF, et al. Malabsorption of Vitamin B12 and Intrinsic Factor Secretion During Biguanide Therapy. Diabetologia. Jan1983;24(1):16-18.
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