How Vitamin B12 interacts with Oral contraceptives
Interaction Type: Depletions
Interaction Rating: Study Supported
Studies have reported that women taking these medications have decreased levels of vitamin B12 in the body. Supplementation with the affected nutrient may be necessary.(1)
These drugs include norethindrone, ethynodiol diacetate, norgestrel, norgestimate, ethinyl estradiol, drospirenone, desogestrel, levonorgestrel.
 
References
  1. View Abstract:  Webb JL. Nutritional Effects of Oral Contraceptive Use: A Review. J Reprod Med. Oct1980;25(4):150-56.
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