How Vitamin B6 interacts with isoniazid
Interaction Type: Depletions
Interaction Rating: Study Supported
This medication is reported to cause decreased vitamin B6 levels in the body, which may result in a tingling, numb, yet sometimes painful sensation in the hands and feet. Supplementation with the affected nutrient may be necessary.(1), (1), (1)
 
References
  1. View Abstract:  Matsui MS, Rozovski SJ. Drug-nutrient Interaction. Clin Ther. 1982;4(6):423-40.
  2. View Abstract:  Snider DE Jr. Pyridoxine Supplementation During Isoniazid Therapy. Tubercle. Dec1980;61(4):191-6.
  3. View Abstract:  Siskind MS, Thienemann D, Kirlin L. Isoniazid-induced neurotoxicity in chronic dialysis patients: report of three cases and a review of the literature. Nephron. 1993;64(2):303-306.
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