How Coenzyme Q10 (CO-Q10) interacts with Biguanides
Interaction Type: Depletions
Interaction Rating: Study Supported

Phenformin has been reported to decrease the formation of coenyzme-Q10 in the body. Supplementation with the affected nutrient may be necessary.(1)
These drugs include metformin.
 
References
  1. View Abstract:  Kishi T, et al. Bioenergetics in Clinical Medicine XI. Studies on Coenzyme Q and Diabetes Mellitus. J Med. 1976;7(3-4):307-21.
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