| Within the framework of a case observation study involving more than
800 general practitioners, more than 5,000 patients with chronic
venous insufficiency (CVI) were treated with standardised horse
chestnut extract and followed up at regular intervals. The evolution
of the symptoms, tolerability and adverse drug reactions were
recorded. All of the symptoms investigated-pain, tiredness, tension
and swelling in the leg, as well as itching and the tendency towards
edema-all improved markedly or disappeared completely. The results of
this study show that rational treatment with horse chestnut extract
represents an economical, practice-relevant therapeutic "pillar",
which in comparison with compression has the additional advantage of
better compliance.
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